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About Us  

We seek to develop, optimize, and apply next-generation molecular genetic technologies to understand gene or gene regulatory network function in a variety of disease contexts.

This enables us to identify technological approaches that are specific to unique indications or cell types and those that can be used in large-scale experimentation for surveying all or most of the genome within cells from many different tissues of origin,  all within a single experiment. The knowledge we gain from fundamental research studies can be applied towards the advancement of next-generation therapeutics and the creation of unique cell-based disease models.  

To achieve these goals, we use a variety of technologies including:

transgene delivery (mRNA, transposons, lenti/retrovirus), CRISPR, RNAi, synthetic genes engineering cellular circuits, multiparameter flow cytometry, next-generation genome sequencing, and bioinformatic analyses.


The lab also translates these technologies and fundamental discoveries for clinical application with an emphasis on cell, gene, and nucleic acid-based therapies.


The Lab

Our lab is part of the Research Centre from the Maisonnueuve-Rosemont Hospital (CR=HMR), integrated to the Health and Social Services of the Island

of Montreal (CIUSSS) and affiliated to the University of Montreal.


Département d'ophtalmologie, Université de Montréal Centre de recherche de l'Hôpital Maisonneuve-Rosemont
Pavillon Claudine D'Amours
5415 Boul.
de l'Assomption
Montréal, QC, Canada H1T 2M4

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